How do Polynucleotides Work?
Polynucleotides are long chains of nucleotides—the building blocks of DNA. When introduced into the skin through injections, they stimulate fibroblast activity, leading to increased production of collagen and elastin. This process promotes tissue regeneration, improves skin elasticity, and enhances hydration. Additionally, polynucleotides possess anti-inflammatory properties and act as antioxidants, scavenging free radicals that contribute to skin aging.
Benefits of Polynucleotide Injections
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Skin Rejuvenation: Enhance skin texture and tone, reducing the appearance of fine lines and wrinkles. 
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Improved Elasticity: Boost collagen and elastin production, leading to firmer skin. 
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Hydration: Increase skin hydration by attracting water molecules, resulting in a plumper appearance. 
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Anti-Inflammatory Effects: Soothe irritated skin, beneficial for conditions like rosacea and eczema. 
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Antioxidant Properties: Protect skin cells from damage caused by free radicals. 
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Treatment Areas
Polynucleotide injections are versatile and can be applied to various areas, including:
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Face: Address fine lines, wrinkles, and overall skin texture. 
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Under-Eye Area: Reduce dark circles and improve skin quality. 
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Neck and Décolletage: Enhance skin firmness and reduce signs of aging. 
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Hands: Improve skin texture and reduce the appearance of veins. 
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Scalp: Support hair follicle health and potentially aid in hair restoration. 
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Procedure Overview
The treatment involves injecting the polynucleotide solution directly into the dermis, the middle layer of the skin. A local anesthetic cream is typically applied beforehand to minimize discomfort. The procedure is relatively quick, and most patients tolerate it well. Some redness or tiny bumps at the injection sites may appear, but there’s very little downtime, and most people resume their routine immediately.
Expected Results and Duration
Patients often notice improvements in skin texture and hydration within a few weeks. Optimal results are typically observed around 12 weeks post-treatment, with effects lasting approximately six to twelve months. Maintenance treatments are recommended annually to preserve the skin’s youthful appearance.
Safety and Considerations
Polynucleotide treatments are generally safe with minimal side effects. Common reactions include mild swelling or bruising at the injection site, which usually fades within 1-2 days. However, due to their animal-derived origin, they are unsuitable for vegetarians, vegans, or individuals with fish allergies. Additionally, they are not recommended during pregnancy or while breastfeeding.
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